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Acute LeukemiasALL predominates as the most common malignancy in children, with a peak incidence from ages 3 to 5 yr. It also occurs in adolescents and less commonly in adults. |
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Allergic PurpuraThe disease affects primarly young children, but older children and adults with allergic purpura are also seen. An acute respiratory infection precedes the purpura in a high proportion of affected young children. Less commonly, a drug appears to be the in |
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Idiopathic Thrombocytopenic Purpura (ITP)In children, usually a self-limited disorder that follows a viral infection; in most adults, a chronic disorder with no apparent predisposing cause. In childhood ITP, viral antigen (Ag) is thought to trigger synthesis of antibody (Ab) that may react with |
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Iron-Deficiency AnemiaThe primary mechanism for Fe deficiency, the most common cause of anemia, must always be considered to be blood loss; in adults this is virtually the only possible mechanism. In men, the most frequent cause is chronic occult bleeding, usually from the GI |
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LeukemiasAlthough viruses cause several forms of leukemia in animals, the cause in humans is undefined; only 2 viral assocations are identified: The Epstein-Barr virus is associated with Burkitt's lymphoma and the human T-cell lymphotropic virus, has been linked t |
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Rhesus Iso-immunisationThe occurrence of perinatal deaths or serious morbidity due to Rhesus iso-immunisation has become less frequent over the past 3 decades. The accessibility and widespread use of anti-D immunoglobulin (anti-D lg) is the single most important factor contribu |
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